Molecular‐Detailed Modeling of Erythrocyte Membrane
نویسندگان
چکیده
منابع مشابه
Localization of Erythrocyte Membrane
The reactions of three organic mercurial compounds, chlormerodrin, parachloromercuribenzoate (PCMB), and parachloromercuribenzenesulfonate (PCMBS) with intact red blood cells, hemolyzed red cells, hemoglobin solutions, and hemoglobin-free ghosts have been characterized. Both PCMB and PCMBS react with only 2 to 3 sulfhydryl groups per mole of hemoglobin in solution, whereas chlormerodrin reacts ...
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The effect of blood lead on erythrocyte membrane proteins was studied in 28 workers from a scrap lead refining factory and in 18 controls working in railway construction. Sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) of the polypeptides in the erythrocyte membrane showed that bands 3 and 4-1 had significantly decreased while bands 2.3, 6, and 7 had significantly increase...
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A cytosolic protein carboxyl methyltransferase (Sadenosyl-L-methi0nine:protein O-methyltransferase, E.C. 2.1.1.24) purified from human erythrocytes catalyzes the methylation of erythrocyte membrane proteins in vitro using S-adenosyl-~-[methyZ-~H]methionine as the methyl group donor. The principal methylaccepting proteins have been identified by sodium dodecyl sulfate-gel electrophoresis at pH 2...
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his study was conducted to investigate the values of the order parameter (S) and correlation time (τc) in electron spin resonance spectra for 5-DS(doxylstearic acid) and 16-DS (doxyl-stearic acid) in old normal controls and in patients with type 2 diabetes and stroke in order to assess any association between age-related disorders and membrane fluidity. Materials and Methods: We measured the me...
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A B S T R A C T Cetiedil has been reported to relieve painful crises in sickle cell anemia and to have antisickling properties in vitro. The drug alters neither oxygen affinity nor the solubility of deoxyhemoglobin S. Because the viscosity of the erythrocyte interior and the kinetics ofgelation are dependent on the concentration of hemoglobin, we postulated that cetiedil might inhibit sickling ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.1218.10